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Rabbit Anti-RANBP3L  antibody (bs-24134R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號(hào) bs-24134R
英文名稱 Rabbit Anti-RANBP3L  antibody
中文名稱 Ran結(jié)合蛋白3樣蛋白抗體
別    名 Ran-binding protein 3-like; Ranbp3l; RNB3L_MOUSE.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 52kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse RANBP3L: 331-430/491 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 RANBP3L (RAN Binding Protein 3 Like) is a Protein Coding gene. An important paralog of this gene is RANBP3.

Function:
Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner.

Subunit:
Interacts with SMAD1, SMAD5 and SMAD8.

SWISS:
Q6PDH4

Gene ID:
223332

Database links:

Entrez Gene: 202151 Human

Entrez Gene: 223332 Mouse

SwissProt: Q86VV4 Human

SwissProt: Q6PDH4 Mouse

Unigene: 729817 Human



產(chǎn)品圖片
Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-RANBP3L (bs-24134R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
Sample: Cerebellum (Mouse) Lysate at 40 ug Primary: Anti-RANBP3L (bs-24134R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RANBP3L) Polyclonal Antibody, Unconjugated (bs-24134R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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