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Rabbit Anti-ELP3  antibody (bs-20539R)  
~~~促銷代碼KT202411~~~
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200ul/2800.00元
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產(chǎn)品編號 bs-20539R
英文名稱 Rabbit Anti-ELP3  antibody
中文名稱 組蛋白乙酰轉(zhuǎn)移酶KAT9抗體
別    名 ELP3_HUMAN; Elongator complex protein 3; EC:2.3.1.-; hELP3; tRNA uridine(34) acetyltransferase; elongator acetyltransferase complex subunit 3; KAT9;   
Specific References  (1)     |     bs-20539R has been referenced in 1 publications.
[IF=5.753] Xiaojun Zhang. et al. TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose‐6‐phosphate dehydrogenase (G6PD). 2021 Feb 25  IP ;  Human.  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELP3: 1-100/547 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Function:
Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the ELP3 family.
Contains 1 N-acetyltransferase domain.

SWISS:
Q9H9T3

Gene ID:
55140

Database links:

Entrez Gene: 55140 Human

Entrez Gene: 74195 Mouse

SwissProt: Q9H9T3 Human

SwissProt: Q9CZX0 Mouse



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