| 產(chǎn)品編號(hào) | bs-20558R |
| 英文名稱 | Rabbit Anti-NCOA2/KAT13C antibody |
| 中文名稱 | 類固醇受體激活蛋白2抗體 |
| 別 名 | glucocorticoid receptor interacting protein 1; GRIP 1; GRIP1; MED1; MGC138808; NCoA 2; nuclear receptor coactivator 2; Oncogene FGR; p160; SRC 2; src2; Steroid receptor coactivator 2; TIF 2; TIF2; Transcriptional intermediary factor 2; NCOA2_HUMAN. |
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Specific References (1) | bs-20558R has been referenced in 1 publications.
[IF=5.157] Hai-Long Zhang. et al. SRC3 Acetylates Calmodulin in the Mouse Brain to Regulate Synaptic Plasticity and Fear Learning. J Biol Chem. 2021 Aug;:101044 WB ; Human, Mouse.
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| 研究領(lǐng)域 | 腫瘤 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 159kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NCOA2/KAT13C: 601-700/1424 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is KAT13C / nuclear receptor coactivator 2 (NCOA2), also termed Glucocorticoid receptor-interacting protein 1 (GRIP1). Subcellular Location: Nucleus. Similarity: Belongs to the SRC/p160 nuclear receptor coactivator family. Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 PAS (PER-ARNT-SIM) domain. SWISS: Q15596 Gene ID: 10499 Database links: Entrez Gene: 10499 Human Omim: 601993 Human SwissProt: Q15596 Human Unigene: 446678 Human |
| 產(chǎn)品圖片 |
Sample:Liver (Mouse)Lysate at 40 ug
Primary: Anti-NCOA2'KAT13C(bs-20558R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 159kD
Observed band size: 159kD
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