| 產(chǎn)品編號 | bs-20312R |
| 英文名稱 | Rabbit Anti-Magphinin antibody |
| 中文名稱 | 卵母細(xì)胞TRO抗體 |
| 別 名 | KIAA1114; MAGE d3; TROP_HUMAN; MAGE D3 antigen; MAGE superfamily protein; MAGED3; Magphinin; Melanoma Antigen Family D, 3; OTTHUMP00000180629; OTTHUMP00000180636; TRO. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 發(fā)育生物學(xué) 細(xì)胞粘附分子 腫瘤細(xì)胞生物標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 144kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Magphinin: 1301-1400/1431 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a membrane protein that mediates apical cell adhesion between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during the process of embryo implantation. This gene is related to the MAGED gene family by sequence similarity and chromosome location. Multiple alternatively spliced transcript variants have been found for this gene; however, the full-length nature of some variants has not been defined. Trophinin is directly responsible for homophilic cell adhesion, and could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Function: Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion. Subunit: Directly binds bystin, and indirectly tastin. Tissue Specificity: Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages. Similarity: Contains 1 MAGE domain. SWISS: Q12816 Gene ID: 56191 Database links: Entrez Gene: 56191 Human Entrez Gene: 7216 Human Omim: 300132 Human SwissProt: Q12816 Human |
