產(chǎn)品編號(hào) | bs-11664R |
英文名稱 | Rabbit Anti-LRRC10 antibody |
中文名稱 | 富含亮氨酸重復(fù)蛋白10抗體 |
別 名 | HRLRRP; leucine-rich repeat-containing protein 10; Leucine-rich repeat-containing protein 10 Gene names; Leucine-rich repeat-containing protein 10 Gene names; LRRC10A; LRC10_HUMAN. |
研究領(lǐng)域 | 心血管 免疫學(xué) 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 32kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LRRC10: 101-200/277 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. LRRC10 (leucine-rich repeat-containing protein 10), also known as HRLRRP or LRRC10A, is a 277 amino acid protein that contains eight LRR repeats. Localized to the nucleus, LRRC10 may play an important role in cardiac development and/or cardiac function. The gene that encodes LRRC10 maps to human chromosome 12q15 and murine chromosome 10 D2. Function: May play important roles in cardiac development and/or cardiac function (By similarity). Subcellular Location: Nucleus Similarity: Contains 7 LRR (leucine-rich) repeats. SWISS: Q5BKY1 Gene ID: 376132 Database links: Entrez Gene: 376132 Human Entrez Gene: 237560 Mouse Omim: 610846 Human SwissProt: Q5BKY1 Human SwissProt: Q3UQT4 Mouse |