| 產(chǎn)品編號(hào) | bs-20292R |
| 英文名稱 | Rabbit Anti-TSPAN6 antibody |
| 中文名稱 | 四分子交聯(lián)體6抗體（四旋蛋白） |
| 別 名 | Putative NF kappa B activating protein 321; Putative NF-kappa-B-activating protein 321; T245; T245 protein; Tetraspan TM4SF; Tetraspanin 6; Tetraspanin TM4 D; Tetraspanin TM4-D; Tetraspanin TM4D; Tetraspanin-6; Tm4sf; TM4SF6; Transmembrane 4 superfamily member 6; TSN6_HUMAN; TSPAN 6; Tspan-6; TSPAN6; Tspan6 protein. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 染色質(zhì)和核信號(hào) 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 28kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TSPAN6: 1-100/245 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. Members of the tetraspanin family are characterized by the presence of four hydrophobic domains and play a role in cell development, activation, growth and motility. TSPAN6 (tetraspanin-6), also known as A15 homolog, putative NF-kappa-B-activating protein 321, T245 protein, tetraspanin TM4-D or TM4SF6 (transmembrane 4 superfamily member 6), is a 245 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. TSPAN6 is expressed at high levels in brain, with lower levels of expression found in colon, lung, pancreas, prostate, retina and melanocytes, as well as fetal heart, liver and spleen. The gene encoding TSPAN6 maps to the human X chromosome. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the tetraspanin (TM4SF) family. SWISS: O43657 Gene ID: 7105 Database links: Entrez Gene: 7105 Human Omim: 300191 Human SwissProt: O43657 Human Unigene: 43233 Human |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (mouse heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TSPAN6) Polyclonal Antibody, Unconjugated (bs-20292R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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