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Rabbit Anti-SLC26A9  antibody (bs-21248R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-21248R
英文名稱 Rabbit Anti-SLC26A9  antibody
中文名稱 溶質載體轉運蛋白家族26成員9抗體
別    名 Anion transporter/exchanger 9; Anion transporter/exchanger protein 9; Solute carrier family 26 member 9.  
研究領域 腫瘤  細胞生物  信號轉導  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 87kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC26A9: 501-600/791 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. The product of this gene is a highly selective chloride ion channel regulated by WNK kinases. Alternative splicing results in multiple transcript variants encoding differing isoforms.[provided by RefSeq, Dec 2008]

Function:
DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion. Inhibited by ammonium and thiosulfate.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in stomach and trachea. Abundantly expressed in the apical domain of the surface epithelial cells and the deep cells in the gastric gland. Also expressed in heart, brain, lung and liver.

Similarity:
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
Contains 1 STAS domain.

SWISS:
Q7LBE3

Gene ID:
115019

Database links:

Entrez Gene: 115019 Human

Entrez Gene: 320718 Mouse

Entrez Gene: 304784 Rat

Omim: 608481 Human

SwissProt: Q7LBE3 Human

SwissProt: Q8BU91 Mouse



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