| 產(chǎn)品編號(hào) | bs-21185R |
| 英文名稱 | Rabbit Anti-SHISA5 antibody |
| 中文名稱 | SHISA5蛋白抗體 |
| 別 名 | pProtein shisa 5; Putative NF kappa B activating protein 120; Putative NFkB activating protein 120; Scotin; Shisa homolog 5 (Xenopus laevis); SHSA5_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞凋亡 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 26kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SHISA5: 41-140/240 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] Function: Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis. Subunit: Interacts with PDCD6; PDCD6 can stabilze SHISA5. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane. DISEASE: Induced in a p53/TP53-dependent manner in response to cellular stress SWISS: Q8N114 Gene ID: 51246 Database links: Entrez Gene: 51246 Human Omim: 607290 Human SwissProt: Q8N114 Human Unigene: 414579 Human |
| 產(chǎn)品圖片 |
Sample:
Spleen (Mouse) Lysate at 40 ug
Primary: Anti-SHISA5 (bs-21185R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD
Sample:
A549(Human) Cell Lysate at 30 ug
Primary: Anti-SHISA5 (bs-21185R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD
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