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Rabbit Anti-SEC31B  antibody (bs-4454R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號(hào) bs-4454R
英文名稱 Rabbit Anti-SEC31B  antibody
中文名稱 轉(zhuǎn)運(yùn)蛋白SEC31B抗體
別    名 SEC31L2; Gm341; Protein transport protein Sec31B; SC31B_HUMAN; SEC31 B; SEC31 homolog B (S. cerevisiae); SEC31 homolog B; SEC31 like 2; SEC31 related protein B; SEC31-like protein 2; SEC31-related protein B; SEC31B 1; SEC31B; SEC31B-1; SEC31L2; Secretory pathway component Sec31B 1; secretory pathway component Sec31B1.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 129kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC31B: 481-580/1179 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site. [provided by RefSeq, Jul 2008]

Function:
As a component of the coat protein complex II (COPII), may function in vesicle budding and cargo export from the endoplasmic reticulum.

Subcellular Location:
Cytoplasm. Cytoplasmic vesicle > COPII-coated vesicle membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Ubiquitously expressed at low levels with specific expression in thymus and testis. Expressed in testis by Sertoli cells, Leydig cells and spermatogonia and in cerebellum more prominently by Purkinje and granular cells (at protein level).

Post-translational modifications:
Monoubiquitinated by the BCR(KLHL12) E3 ubiquitin ligase complex, leading to regulate the size of COPII coats.

Similarity:
Belongs to the WD repeat SEC31 family.
Contains 8 WD repeats.

SWISS:
Q9NQW1

Gene ID:
25956

Database links:

Entrez Gene: 25956 Human

Entrez Gene: 240667 Mouse

Entrez Gene: 309433 Rat

Omim: 610258 Human

SwissProt: Q9NQW1 Human

SwissProt: Q3TZ89 Mouse

Unigene: 18889 Human

Unigene: 329873 Mouse



產(chǎn)品圖片
Sample: Hela(Human) Cell Lysate at 30 ug SY5Y(Human) Cell Lysate at 30 ug Primary: Anti- SEC31B (bs-4454R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 129 kD Observed band size: 129 kD
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