| 產(chǎn)品編號(hào) | bs-8010R |
| 英文名稱 | Rabbit Anti-WNT 5B antibody |
| 中文名稱 | 信號(hào)通路Wnt-5B抗體 |
| 別 名 | MGC2648; Wnt5b; Protein Wnt-5b; Wingless type MMTV integration site family, member 5B; WNT 5B; WNT 5B protein; Wnt5b; WNT5B protein; WNT5B_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 干細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human WNT5B: 201-300/359 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Subunit: Interacts with PORCN. Subcellular Location: Secreted > extracellular space > extracellular matrix. Similarity: Belongs to the Wnt family. SWISS: Q9H1J7 Gene ID: 81029 Database links: Entrez Gene: 81029 Human Entrez Gene: 22419 Mouse Entrez Gene: 100349579 Rabbit Entrez Gene: 30105 Zebrafish Omim: 606361 Human SwissProt: Q9H1J7 Human SwissProt: P22726 Mouse SwissProt: Q92050 Zebrafish Unigene: 306051 Human Unigene: 321818 Mouse Unigene: 58724 Rat Unigene: 389 Zebrafish |
| 產(chǎn)品圖片 |
Sample:Bladder (Mouse)Lysate at 40 ug
Primary: Anti- WNT 5B(bs-8010R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 38kD
Observed band size: 38kD
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