產(chǎn)品編號 | bs-12764R |
英文名稱 | Rabbit Anti-PNPLA8 antibody |
中文名稱 | 磷脂酶patatin樣域包含蛋白8抗體 |
別 名 | Calcium-independent phospholipase A2-gamma; Intracellular membrane associated calcium independent phospholipase A2 gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; IPLA2 2; iPLA2 gamma; IPLA2(GAMMA); iPLA2-2; iPLA2-gamma; IPLA22; IPLA2G; Patatin like phospholipase domain containing protein 8; Patatin-like phospholipase domain-containing protein 8; PLPL8_HUMAN; PNPLA-gamma; PNPLA8. |
研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,GuineaPig,Horse) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 88kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PNPLA8: 601-700/782 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Function: Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids. Subcellular Location: Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > perinuclear region. Tissue Specificity: Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart. Similarity: Contains 1 patatin domain. SWISS: Q9NP80 Gene ID: 50604 Database links: Entrez Gene: 50640 Human Entrez Gene: 67452 Mouse Omim: 612123 Human SwissProt: Q9NP80 Human SwissProt: Q8K1N1 Mouse Unigene: 617340 Human Unigene: 732217 Human Unigene: 54126 Mouse Unigene: 23073 Rat |