| 產(chǎn)品編號(hào) | bs-12680R |
| 英文名稱 | Rabbit Anti-ValRS antibody |
| 中文名稱 | 纈氨酰-tRNA合成酶1抗體 |
| 別 名 | Bat 6; Bat6; D17H6S56E; EC 6.1.1.9; G7A; Protein G7a; SYVC_HUMAN; valine tRNA ligase 1, cytoplasmic; Valine tRNA ligase; Valine--tRNA ligase; ValRS; VALYL tRNA SYNTHETASE 1; valyl tRNA synthetase 2; valyl-tRNA synthetase 2; Valyl-tRNA synthetase; VARS; Vars1; VARS2; VARS2, formerly. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Dog,Horse,Danio) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 140kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ValRS: 401-500/1264 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008] DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:A disorder due to mitochondrial respiratory chain complex defects. Clinical features are variable and include muscle weakness with hypotonia, central neurological disease with progressive external ophthalmoplegia, ptosis and ataxia, delayed psychomotor development, cardiomyopathy, abnormal liver function, facial dysmorphism, microcephaly and epilepsy. Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. Contains 1 GST C-terminal domain. SWISS: P26640 Gene ID: 7407 Database links: Entrez Gene: 7407 Human Entrez Gene: 22321 Mouse Omim: 192150 Human SwissProt: P26640 Human SwissProt: Q9Z1Q9 Mouse Unigene: 520026 Human Unigene: 28420 Mouse Unigene: 12314 Rat |
