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Rabbit Anti-PFDN5  antibody (bs-12629R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-12629R
英文名稱 Rabbit Anti-PFDN5  antibody
中文名稱 前折疊蛋白亞基5抗體
別    名 1190001O17Rik; 1700010A06Rik; c myc binding protein; c-myc binding protein MM 1; C-myc-binding protein Mm-1; D15Ertd697e; EIG 1; Eig1; MGC5329; MGC71907; MM 1; MM1; Myc modulator 1; PFD5; PFD5_HUMAN; PFDN5; Prefoldin 5; Prefoldin subunit 5.  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Zebrafish,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PFDN5: 1-100/154 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Tissue Specificity:
Highly expressed in pancreas and skeletal muscle and moderately in other tissues.

Similarity:
Belongs to the prefoldin subunit alpha family.

SWISS:
Q99471

Gene ID:
5204

Database links:

Entrez Gene: 5204 Human

Entrez Gene: 56612 Mouse

Entrez Gene: 300257 Rat

Omim: 604899 Human

SwissProt: Q99471 Human

SwissProt: Q9WU28 Mouse

Unigene: 655327 Human

Unigene: 158264 Mouse

Unigene: 3401 Rat



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