| 產(chǎn)品編號(hào) | bs-21057R |
| 英文名稱 | Rabbit Anti-PPFIBP1 antibody |
| 中文名稱 | PTPRF相互作用蛋白結(jié)合蛋白1抗體 |
| 別 名 | PPFIBP 1; hSGT2; hSgt2p; KIAA1230; KIAA1230; L2; LIPB1_HUMAN; Liprin beta 1; liprin related protein; Liprin-beta-1; PPFIBP 1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein binding protein 1; PTPRF interacting protein, binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 結(jié)合蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Zebrafish,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 114kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PPFIBP1: 701-800/1011 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Function: May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A. Tissue Specificity: Widely expressed. Absent in liver. Similarity: Belongs to the liprin family. Liprin-beta subfamily. Contains 3 SAM (sterile alpha motif) domains. SWISS: Q86W92 Gene ID: 8496 Database links: Entrez Gene: 100064684 Horse Entrez Gene: 8496 Human Entrez Gene: 67533 Mouse Omim: 603141 Human SwissProt: Q86W92 Human SwissProt: Q8C8U0 Mouse Unigene: 172445 Human Unigene: 103382 Mouse Unigene: 22871 Rat |
