| 產(chǎn)品編號 | bs-21007R |
| 英文名稱 | Rabbit Anti-PAIP2 antibody |
| 中文名稱 | 多聚腺苷酸結(jié)合蛋白相互作用蛋白2抗體 |
| 別 名 | PABP-interacting protein 2; PAIP-2; PAIP2; PAIP2_HUMAN; poly(A) binding protein interacting protein 2; Poly(A)-binding protein-interacting protein 2; Polyadenylate-binding protein-interacting protein 2. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 結(jié)合蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 15kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAIP2: 51-127/127 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PAIP2 (Poly(A) Binding Protein Interacting Protein 2) is a Protein Coding gene. Among its related pathways are Translational Control and TGF-Beta Pathway. GO annotations related to this gene include mRNA binding and translation repressor activity. An important paralog of this gene is PAIP2B. Function: Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. Subunit: Interacts with the RRM1-RRM2 and C-terminus regions of PABPC1 in a 1:1 stoichiometry. Interacts with EIF4A. Subcellular Location: Cytoplasm. Similarity: Belongs to the PAIP2 family. SWISS: Q9BPZ3 Gene ID: 51247 Database links: Entrez Gene: 416187 Chicken Entrez Gene: 51247 Human Entrez Gene: 67869 Mouse Omim: 605604 Human SwissProt: Q5ZJS6 Chicken SwissProt: Q9BPZ3 Human SwissProt: Q9D6V8 Mouse Unigene: 396644 Human Unigene: 126534 Mouse Unigene: 1073 Rat |
