| 產(chǎn)品編號 | bs-19991R |
| 英文名稱 | Rabbit Anti-PPP1R1C antibody |
| 中文名稱 | 蛋白磷酸酶1調(diào)節(jié)亞基1c抗體 |
| 別 名 | Inhibitor 5 of protein phosphatase 1; IPP5; PP1 inhibitor protein 5; Ppp1r1c; PPR1C_HUMAN; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1, regulatory (inhibitor) subunit 1C. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 12kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PPP1R1C: 1-100/567 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] Function: Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. Subcellular Location: Cytoplasm. Tissue Specificity: Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level). Post-translational modifications: Phosphorylation at Ser-56 favors interaction with CALM1. Isoform 1 is methylated by CARM1 in immature thymocytes. Similarity: Contains 1 R3H domain. SWISS: Q8WVI7 Gene ID: 151242 Database links: Entrez Gene: 10777 Human Entrez Gene: 74100 Mouse Omim: 605488 Human SwissProt: Q9UBL0 Human SwissProt: Q9DCB4 Mouse Unigene: 475902 Human Unigene: 713605 Human Unigene: 297444 Mouse |
