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Rabbit Anti-phospho-RGS16 (Tyr168)  antibody (bs-19856R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-19856R
英文名稱 Rabbit Anti-phospho-RGS16 (Tyr168)  antibody
中文名稱 磷酸化G蛋白信號轉(zhuǎn)導調(diào)節(jié)因子16抗體
別    名 RGS16 (phospho Y168); p-RGS16 (phospho Y168); A28 RGS14; A28 RGS14P; A28-RGS14P; HGNC:9997; hRGS-r; OTTHUMP00000033147; Regulator of G protein signaling 16; Regulator of G protein signalling 16; Regulator of G-protein signaling 16; Retinal-specific RGS; Retinally abundant regulator of G protein signaling; Retinally abundant regulator of G-protein signaling; RGS 16; RGS R; RGS-R; Rgs14; RGS16; RGS16_HUMAN; RGSR.  
產(chǎn)品類型 磷酸化抗體 
研究領域 細胞生物  信號轉(zhuǎn)導  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 23kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human RGS16 around the phosphorylation site of Tyr168: DS(p-Y)PR 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.

Tissue Specificity:
Abundantly expressed in retina with lower levels of expression in most other tissues.

Post-translational modifications:
Palmitoylated on Cys-2 and/or Cys-12.
Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.

Similarity:
Contains 1 RGS domain.

SWISS:
O15492

Gene ID:
6004

Database links:

Entrez Gene: 6004 Human

Entrez Gene: 19734 Mouse

Omim: 602514 Human

SwissProt: O15492 Human

SwissProt: P97428 Mouse

Unigene: 413297 Human

Unigene: 181709 Mouse



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