| 產(chǎn)品編號 | bs-19839R |
| 英文名稱 | Rabbit Anti-REXO1 antibody |
| 中文名稱 | 轉(zhuǎn)錄延伸因子結(jié)合蛋白1抗體 |
| 別 名 | EloA BP1; ELOABP1; Elongin A binding protein 1; KIAA1138; REX1, RNA exonuclease 1 homolog (S. cerevisiae); RNA exonuclease 1 homolog; TCEB3BP1; Transcription elongation factor B polypeptide 3 binding protein 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 131kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human REXO1: 801-900/1221 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo. Function: Seems to have no detectable effect on transcription elongation in vitro. Subunit: Interacts with TCEA2 and TCEB3. Subcellular Location: Nuclear Similarity: Belongs to the REXO1/REXO3 family. Contains 1 exonuclease domain. SWISS: Q8N1G1 Gene ID: 57455 Database links: Entrez Gene: 57455 Human Omim: 609614 Human SwissProt: Q8N1G1 Human Unigene: 192477 Human |
