| 產(chǎn)品編號(hào) | bs-19733R |
| 英文名稱 | Rabbit Anti-RASEF antibody |
| 中文名稱 | ras基因相關(guān)蛋白R(shí)ab45抗體 |
| 別 名 | FLJ31614; RAB45; RAB45 member RAS oncogene family; RASEF_HUMAN; RAS and EF hand domain containing; RAS and EF hand domain containing protein; Ras related protein Rab 45. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 83kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RASEF: 551-650/740 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the Rab family of GTPases that are involved in regulation of membrane traffic. The encoded protein contains an N-terminal EF-hand domain, a coiled-coil motif and a C-terminal Rab domain. A potential role as tumor suppressor has been indicated for this gene. [provided by RefSeq, Nov 2012] Function: Binds predominantly GDP, and also GTP. Subcellular Location: Cytoplasm, perinuclear region. Tissue Specificity: Down-regulated in cutaneous melanoma cells but not in breast cancer cells. Similarity: Belongs to the small GTPase superfamily. Rab family. SWISS: Q8IZ41 Gene ID: 158158 Database links: Entrez Gene: 158158 Human Entrez Gene: 242505 Mouse Omim: 611344 Human SwissProt: Q8IZ41 Human SwissProt: Q5RI75 Mouse Unigene: 657750 Human Unigene: 487185 Mouse |
