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Rabbit Anti-RTN4RL1  antibody (bs-20071R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-20071R
英文名稱 Rabbit Anti-RTN4RL1  antibody
中文名稱 Nogo66受體相關(guān)蛋白3抗體
別    名 DKFZp547J144; NgR 3; NgR3; NGRH 2; NGRH2; NGRL2; Nogo 66 receptor homolog 2; Nogo 66 receptor related protein 3; Nogo receptor like 2; Reticulon 4 receptor like 1; R4RL1_HUMAN.  
Specific References  (2)     |     bs-20071R has been referenced in 2 publications.
[IF=2.515] Li T et al. Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis. R. Soc. open sci. 2019,6: 181604.  WB&IHC-P ;  Sheep.  
[IF=2.515] Li T et al. Digital gene expression analyses of mammary glands from meat ewes naturally infected with clinical mastitis.R Soc Open Sci. 2019 Jul 3;6(7):181604.  WB&IHC ;  Sheep.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RTN4RL1: 101-300/441 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 NgR3 is a 441 amino acid protein that belongs to the Nogo receptor family. Localized to the cell membrane, NgR3 contains 8 LRR (leucine-rich) repeats. NgR3 is predominantly expressed in brain, where it localizes to the surface of neurons, but is also found at lower levels in lung, placenta, kidney, mammary gland, skeletal muscle, spleen and salivary gland. NgR3 is thought to play a role in the regulation of axonal regeneration and plasticity in the adult central nervous system. The gene that encodes NgR3 maps to human chromosome 17, which makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes.

Function:
RTN4RL1 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor. Note: Localized to the surface of neurons, including axons

Tissue Specificity:
Predominantly expressed in brain. Expressed at lower levels in kidney, lung, mammary gland, placenta, salivary gland, skeletal muscle and spleen.

Similarity:
Belongs to the Nogo receptor family.
Contains 8 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q86UN2

Gene ID:
146760

Database links:

Entrez Gene: 146760 Human

Entrez Gene: 237847 Mouse

Entrez Gene: 303311 Rat

Omim: 610461 Human

SwissProt: Q86UN2 Human

SwissProt: Q8K0S5 Mouse

SwissProt: Q80WD0 Rat

Unigene: Human



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