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Rabbit Anti-NXF3  antibody (bs-19554R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-19554R
英文名稱 Rabbit Anti-NXF3  antibody
中文名稱 核RNA輸出因子3抗體
別    名 Nuclear RNA export factor 3; NXF3; NXF3_HUMAN; OTTHUMP00000023726; OTTHUMP00000023727; TAP like protein 3; TAP-like protein 3; TAPL 3; TAPL-3; TAPL3.  
研究領(lǐng)域 染色質(zhì)和核信號  轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60kDa
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NXF3: 1-100/531 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]

Function:
May function as a tissue-specific nuclear mRNA export factor.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.

Tissue Specificity:
Expressed at high level in testis and at low level in a small number of tissues.

Similarity:
Belongs to the NXF family.
Contains 1 NTF2 domain.
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q9H4D5

Gene ID:
56000

Database links:

Entrez Gene: 56000 Human

Omim: 300316 Human

SwissProt: Q9H4D5 Human

Unigene: 60386 Human



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