| 產(chǎn)品編號 | bs-19543R |
| 英文名稱 | Rabbit Anti-NUP155 antibody |
| 中文名稱 | 核孔復(fù)合蛋白Nup155抗體 |
| 別 名 | 155 kDa nucleoporin; D930027M19Rik; KIAA0791; mKIAA0791; N155; NU155_HUMAN; Nuclear pore complex protein Nup155; nucleoporin 155kD; Nucleoporin Nup155; Nup155. |
| 研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Zebrafish) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 155kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NUP155: 201-300/1391 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013] Function: Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport. Subcellular Location: Nucleus > nuclear pore complex. Nucleus membrane. Nucleus membrane. In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis. Tissue Specificity: Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Post-translational modifications: Phosphorylated. Phosphorylation and dephosphorylation may be important for the function of NUP155 and may play a role in the reversible disassembly of the nuclear pore complex during mitosis. Similarity: Belongs to the non-repetitive/WGA-negative nucleoporin family. SWISS: O75694 Gene ID: 9631 Database links: Entrez Gene: 9631 Human Entrez Gene: 427443 Chicken Entrez Gene: 461913 Chimpanzee Entrez Gene: 101133763 Gorilla Entrez Gene: 100053405 Horse Entrez Gene: 170762 Mouse Entrez Gene: 100437988 Orangutan Entrez Gene: 100347238 Rabbit Entrez Gene: 706019 Rhesus monkey Entrez Gene: 380494 Xenopus laevis Entrez Gene: 100379911 Xenopus tropicalis Omim: 606694 Human SwissProt: O75694 Human SwissProt: Q99P88 Mouse Unigene: 547696 Human Unigene: 295168 Mouse Unigene: 11328 Rat |
