產(chǎn)品編號 | bs-19499R |
英文名稱 | Rabbit Anti-Nfe2l3 antibody |
中文名稱 | NFE2相關(guān)因子樣蛋白3抗體 |
別 名 | erythroid derived 2; like 3; NF-E2-related factor 3; NF2L3_HUMAN; NFE2-related factor 3; Nfe2l3; NRF3; Nuclear factor; Nuclear factor erythroid 2-related factor 3. |
研究領(lǐng)域 | 細胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 76kDa |
細胞定位 | 細胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Nfe2l3: 481-580/694 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009] Function: Activates erythroid-specific, globin gene expression. Subunit: Heterodimer with MAFG, MAFK and other small MAF proteins that binds to the MAF recognition elements (MARE). Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas. Similarity: Belongs to the bZIP family. CNC subfamily. Contains 1 bZIP domain. SWISS: Q9Y4A8 Gene ID: 9603 Database links: Entrez Gene: 9603 Human Omim: 604135 Human SwissProt: Q9Y4A8 Human Unigene: 404741 Human Unigene: 712898 Human |