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Rabbit Anti-Nfe2l3  antibody (bs-19499R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-19499R
英文名稱 Rabbit Anti-Nfe2l3  antibody
中文名稱 NFE2相關(guān)因子樣蛋白3抗體
別    名 erythroid derived 2; like 3; NF-E2-related factor 3; NF2L3_HUMAN; NFE2-related factor 3; Nfe2l3; NRF3; Nuclear factor; Nuclear factor erythroid 2-related factor 3.  
研究領(lǐng)域 細胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Cow)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 76kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nfe2l3: 481-580/694 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]

Function:
Activates erythroid-specific, globin gene expression.

Subunit:
Heterodimer with MAFG, MAFK and other small MAF proteins that binds to the MAF recognition elements (MARE).

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in human placenta and also in B-cell and monocyte cell lines. Low expression in heart, brain, lung, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the bZIP family. CNC subfamily.
Contains 1 bZIP domain.

SWISS:
Q9Y4A8

Gene ID:
9603

Database links:

Entrez Gene: 9603 Human

Omim: 604135 Human

SwissProt: Q9Y4A8 Human

Unigene: 404741 Human

Unigene: 712898 Human



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