產(chǎn)品編號(hào) | bs-19433R |
英文名稱 | Rabbit Anti-PRRG1 antibody |
中文名稱 | 跨膜γ羧基酸蛋白1抗體 |
別 名 | PRGP1; Proline rich gamma carboxyglutamic acid protein 1; Proline rich Gla (G carboxyglutamic acid) 1; Proline rich Gla (G carboxyglutamic acid) polypeptide 1; Proline rich Gla protein 1; Proline-rich gamma-carboxyglutamic acid protein 1; Proline-rich Gla protein 1; PRRG1; TMG1; TMG1_HUMAN; Transmembrane gamma carboxyglutamic acid protein 1 [Precursor]; Transmembrane gamma-carboxyglutamic acid protein 1. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 23kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PRRG1: 21-100/318 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010] Subcellular Location: Membrane. Tissue Specificity: Highly expressed in the spinal cord. Post-translational modifications: Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase. Similarity: Contains 1 Gla (gamma-carboxy-glutamate) domain. SWISS: O14668 Gene ID: 5638 Database links: Entrez Gene: 5638 Human Entrez Gene: 546336 Mouse Omim: 604428 Human SwissProt: O14668 Human Unigene: 190341 Human |