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Rabbit Anti-NPAS4  antibody (bs-19325R)  
~~~促銷(xiāo)代碼KT202411~~~
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說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19325R
英文名稱 Rabbit Anti-NPAS4  antibody
中文名稱 神經(jīng)細(xì)胞PAS結(jié)構(gòu)域蛋白4抗體
別    名 bHLH PAS type transcription factor NXF; bHLHe79; bHLHe79; Class E basic helix-loop-helix protein 79; HLH-PAS transcription factor NXF; Le PAS; limbic enhanced PAS protein; neuronal PAS domain protein 4; Neuronal PAS domain-containing protein 4; Neuronal PAS4; NPAS4; NPAS4_HUMAN; NXF; PAS domain-containing protein 10; PASD10.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 87kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NPAS4: 1-100/802 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008]

Function:
Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.

Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT.

Subcellular Location:
Nucleus.

Tissue Specificity:
Brain.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 2 PAS (PER-ARNT-SIM) domains.

SWISS:
Q8IUM7

Gene ID:
266743

Database links:

Entrez Gene: 266743 Human

Entrez Gene: 225872 Mouse

Entrez Gene: 266734 Rat

Entrez Gene: 724016 Zebrafish

Omim: 608554 Human

SwissProt: Q8IUM7 Human

SwissProt: Q8BGD7 Mouse

SwissProt: Q8CJH6 Rat

SwissProt: Q1ECW2 Zebrafish

Unigene: 256036 Human

Unigene: 287867 Mouse

Unigene: 86654 Rat

Unigene: 81110 Zebrafish



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