產(chǎn)品編號(hào) | bs-19211R |
英文名稱 | Rabbit Anti-Neurexophilin 3 antibody |
中文名稱 | 神經(jīng)外營(yíng)養(yǎng)蛋白3抗體 |
別 名 | KIAA1159; Neurexophilin-3; NPH3; Nxph3; NXPH-3; NXPH3_HUMAN; UNQ687/PRO1327. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Dog) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 28kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Neurexophilin 3: 1-100/252 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I Alpha(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality. Function: May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins. Subcellular Location: Secreted. Tissue Specificity: Highest level in brain. Post-translational modifications: May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells. Similarity: Belongs to the neurexophilin family. SWISS: O95157 Gene ID: 11248 Database links: Entrez Gene: 11248 Human Entrez Gene: 104079 Mouse Omim: 604636 Human SwissProt: O95157 Human SwissProt: Q91VX5 Mouse Unigene: 55069 Human Unigene: 22970 Mouse Unigene: 19736 Rat |