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Rabbit Anti-Neurexophilin 3  antibody (bs-19211R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19211R
英文名稱 Rabbit Anti-Neurexophilin 3  antibody
中文名稱 神經(jīng)外營(yíng)養(yǎng)蛋白3抗體
別    名 KIAA1159; Neurexophilin-3; NPH3; Nxph3; NXPH-3; NXPH3_HUMAN; UNQ687/PRO1327.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neurexophilin 3: 1-100/252 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I Alpha(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.

Function:
May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins.

Subcellular Location:
Secreted.

Tissue Specificity:
Highest level in brain.

Post-translational modifications:
May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells.

Similarity:
Belongs to the neurexophilin family.

SWISS:
O95157

Gene ID:
11248

Database links:

Entrez Gene: 11248 Human

Entrez Gene: 104079 Mouse

Entrez Gene: 59315 Rat

Omim: 604636 Human

SwissProt: O95157 Human

SwissProt: Q91VX5 Mouse

SwissProt: Q9Z2N5 Rat

Unigene: 55069 Human

Unigene: 22970 Mouse

Unigene: 19736 Rat



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