產(chǎn)品編號(hào) | bs-19196R |
英文名稱 | Rabbit Anti-NRK2/NEK4 antibody |
中文名稱 | 絲氨酸/蘇氨酸蛋白激酶2抗體 |
別 名 | EC 2.7.11.1; MGC33171; Never in mitosis A related kinase 4; Never in mitosis gene A related kinase 4; NIMA (never in mitosis gene a) related kinase 4; NIMA (never in mitosis gene a)-related expressed kinase 4; NIMA related kinase 4; NimA related protein kinase 4; NLK2; NRK2; NEK4_HUMAN; OTTHUMP00000213582; Pp12301; Serine/threonine kinase 2; Serine/threonine protein kinase 2; Serine/threonine protein kinase Nek4; Serine/threonine protein kinase NRK2; STK2. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 95kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NRK2/NEK4: 301-400/841 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
NEK4 (NIMA related kinase 4) is a serine/threonine protein kinase related to the asperigillus NIMA (never in mitosis gene a) kinase. NEK4 is proposed to play a role in cell division. Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, liver, kidney, lung and placenta. Present in most primary carcinomas. There are two named isoforms produced by alternative splicing. Function: Seems to act exclusively upon threonine residues. Subcellular Location: Nuclear Tissue Specificity: Highest expression in adult heart, followed by pancreas, skeletal muscle, brain, liver, kidney, lung and placenta. Present in most primary carcinomas. Similarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. SWISS: P51957 Gene ID: 6787 Database links: Entrez Gene: 6787 Human Omim: 601959 Human SwissProt: P51957 Human Unigene: 631921 Human |