| 產(chǎn)品編號(hào) | bs-19097R |
| 英文名稱 | Rabbit Anti-Multimerin 2 antibody |
| 中文名稱 | Multimerin 2蛋白抗體 |
| 別 名 | Elastin microfibril interface located protein 3; Elastin microfibril interfacer 3; EMILIN like protein EndoGlyx 1; EMILIN-3; EMILIN3; ENDOGLYX 1; EndoGlyx-1; EndoGlyx-1 p125/p140 subunit; ENDOGLYX1; MMRN2; MMRN2_HUMAN; Multimerin-2. |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 102kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Multimerin 2: 361-460/949 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012] Function: Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA. Subcellular Location: Secreted > extracellular space > extracellular matrix. Tissue Specificity: Endothelium. Post-translational modifications: N- and O-glycosylated. Similarity: Contains 1 C1q domain. Contains 1 EMI domain. SWISS: Q9H8L6 Gene ID: 79812 Database links: Entrez Gene: 79812 Human Omim: 608925 Human SwissProt: Q9H8L6 Human Unigene: 524479 Human |
