| 產(chǎn)品編號(hào) | bs-19095R |
| 英文名稱 | Rabbit Anti-NECAP1 antibody |
| 中文名稱 | NECAP1蛋白抗體 |
| 別 名 | Adaptin ear binding coat associated protein 1; Adaptin ear-binding coat-associated protein 1; DKFZP566B183; MGC131900; NECAP 1; NECAP endocytosis associated 1; NECAP endocytosis-associated protein 1; NECAP-1; NECAP1; NECP1_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 30kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NECAP1: 1-100/275 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
NECAP 1 is a 275 amino acid cell membrane protein belonging to the NECAP family that localizes to the clathrin-coated vesicle membrane. NECAP 1 is encoded by a gene that maps to human chromosome 12p13.31 and contains two WXXF motifs that are used to mediate binding of accessory proteins to ear domains of various proteins such as AP-1, AP-2 and GGAs. Expressed primarily in brain and existing as two alternatively spliced isoforms, NECAP 1 colocalizes with AP-2 at the plasma membrane by binding AP-2s alpha-ear domain. Function: Involved in endocytosis. Subcellular Location: Cytoplasmic vesicle > clathrin-coated vesicle membrane. Cell membrane. Colocalizes with AP-2 at the plasma membrane. Similarity: Belongs to the NECAP family. SWISS: Q8NC96 Gene ID: 25977 Database links: Entrez Gene: 67602 Mouse SwissProt: Q9CR95 Mouse Unigene: 52837 Cow Unigene: 288114 Mouse Unigene: 58356 Rat |
