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Rabbit Anti-NAPRT1  antibody (bs-19017R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-19017R
英文名稱 Rabbit Anti-NAPRT1  antibody
中文名稱 煙酸磷酸NAPRT1抗體
別    名 FHA HIT interacting protein; FHA-HIT-interacting protein; FHIP; FHIP; NAPRT1; NAPRTase; Nicotinate phosphoribosyltransferase; Nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; Nicotinic acid phosphoribosyltransferase; PNCB_HUMAN; PP3856.  
研究領域 腫瘤  細胞生物  信號轉導  激酶和磷酸酶  新陳代謝  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAPRT1: 351-450/538 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008]

Function:
Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells.

Tissue Specificity:
Cytoplasm > cytosol.

Similarity:
Belongs to the NAPRTase family.

SWISS:
Q6XQN6

Gene ID:
93100

Database links:

Entrez Gene: 399559 Cow

Entrez Gene: 93100 Human

Entrez Gene: 223646 Mouse

Entrez Gene: 315085 Rat

Entrez Gene: 393864 Zebrafish

Omim: 611552 Human

SwissProt: A5PK51 Cow

SwissProt: Q6XQN6 Human

SwissProt: Q8CC86 Mouse

SwissProt: Q6XQN1 Rat

SwissProt: Q6P3H4 Zebrafish

Unigene: 493164 Human

Unigene: 288368 Mouse

Unigene: 22665 Rat

Unigene: 29094 Zebrafish



產品圖片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-NAPRT1 (bs-19017R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD
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