| 產(chǎn)品編號(hào) | bs-18883R |
| 英文名稱(chēng) | Rabbit Anti-PDE10A antibody |
| 中文名稱(chēng) | 磷酸二酯酶10A抗體 |
| 別 名 | 5''-cyclic phosphodiesterase 10A; cAMP and cAMP inhibited cGMP 3'5' cyclic phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3''; cAMP and cAMP-inhibited cGMP 3'5'-cyclic phosphodiesterase 10A; FLJ11894; HSPDE 10A; HSPDE10A; PDE 10A; PDE10_HUMAN; Pde10a; Phosphodiesterase 10A; Phosphodiesterase 10A1. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 88kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDE10A: 241-340/779 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011] Function: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. Subcellular Location: Cytoplasm. Located mostly to soluble cellular fractions. Tissue Specificity: Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. Contains 2 GAF domains. SWISS: Q9Y233 Gene ID: 10846 Database links: Entrez Gene: 10846 Human Entrez Gene: 23984 Mouse Omim: 610652 Human SwissProt: Q9Y233 Human SwissProt: Q8CA95 Mouse Unigene: 348762 Human Unigene: 87161 Mouse Unigene: 44869 Rat |
