| 產(chǎn)品編號(hào) | bs-18882R |
| 英文名稱(chēng) | Rabbit Anti-MRPS33 antibody |
| 中文名稱(chēng) | 28S核糖體蛋白S33抗體 |
| 別 名 | 28S ribosomal protein S33; 28S ribosomal protein S33, mitochondrial; AI841153; CGI 139; FLJ21123; Ganglioside induced differentiation associated protein 3; Gdap3; MGC106490; mitochondrial; MRP S33; MRP-S33; PTD003; RT33_HUMAN; S33mt. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 13kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RT33/MRPS33: 21-80/106 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008] Function: Displays low GTPase activity and exist predominantly in the GTP-bound form. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side Tissue Specificity: Highly expressed in heart and brain. Similarity: Belongs to the small GTPase superfamily. Di-Ras family. SWISS: Q9Y291 Gene ID: 51650 Database links: Entrez Gene: 51650 Human Entrez Gene: 14548 Mouse Omim: 611993 Human SwissProt: Q9Y291 Human SwissProt: Q9D2R8 Mouse Unigene: 416207 Human Unigene: 377071 Mouse |
