| 產(chǎn)品編號 | bs-18499R |
| 英文名稱 | Rabbit Anti-ZNF711/ZNF5 antibody |
| 中文名稱 | 鋅指蛋白711抗體 |
| 別 名 | CMPX1; dJ75N13.1; MRX97; Zfp711; Zinc finger protein 6 (CMPX1); Zinc finger protein 6; Zinc finger protein 711; ZN711; ZN711_HUMAN; ZNF4; ZNF5; ZNF6; ZNF711. |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 87kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF711/ZNF5: 501-600/761 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with mental retardation. [provided by RefSeq, Jul 2008] Function: Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C. Subcellular Location: Nucleus. Tissue Specificity: Expressed in neural tissues. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. DISEASE: Defects in ZNF711 are the cause of mental retardation X-linked ZNF711-related (MRXZ) [MIM:300803]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 12 C2H2-type zinc fingers. SWISS: Q9Y462 Gene ID: 314990 Database links: Entrez Gene: 7552 Human Entrez Gene: 245595 Mouse Omim: 314990 Human SwissProt: Q9Y462 Human SwissProt: A2ANX9 Mouse Unigene: 326801 Human Unigene: 259846 Mouse |
