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Rabbit Anti-LIN9  antibody (bs-18283R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-18283R
英文名稱 Rabbit Anti-LIN9  antibody
中文名稱 LIN9蛋白抗體
別    名 BARA; Beta subunit-associated regulator of apoptosis; Beta-subunit associated regulator of apoptosis; hLin-9; huLin-9; lin-9; lin9; LIN9_HUMAN; pRB-associated protein; Protein lin-9 homolog; TGS; TUDOR gene similar protein; Type I interferon receptor beta chain-associated protein.  
研究領域 細胞生物  細胞凋亡  細胞周期蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIN9 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Function:
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.

Subcellular Location:
Nucleus > nucleoplasm. Found in perinucleolar structures. Associated with chromatin.

Tissue Specificity:
Expressed in thymus and testis.

Similarity:
Belongs to the lin-9 family.

SWISS:
Q5TKA1

Gene ID:
286826

Database links:

Entrez Gene: 286826 Human

Entrez Gene: 421316 Chicken

Entrez Gene: 72568 Mouse

Entrez Gene: 689523 Rat

Entrez Gene: 323027 Zebrafish

Entrez Gene: 560867 Zebrafish

Omim: 609375 Human

SwissProt: Q5TKA1 Human

SwissProt: Q8C735 Mouse

SwissProt: Q5RHQ8 Zebrafish

Unigene: 120817 Human

Unigene: 275044 Mouse

Unigene: 214693 Rat

Unigene: 76676 Zebrafish



產品圖片
25 ug total protein per lane of various lysates (see on figure) probed with LIN9 polyclonal antibody, unconjugated (bs-18283R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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