| 產(chǎn)品編號(hào) | bs-18226R |
| 英文名稱(chēng) | Rabbit Anti-PENK(237-258) antibody |
| 中文名稱(chēng) | 腦啡肽A抗體 |
| 別 名 | EP-ENK; Enkephalin A; P ENK; Preproencephalin A; Proenkephalin A; Proenkephalin; Synenkephalin; Proenkephalin; Opioid growth factor; OGF; PENK protein; ProenkephalinA; PENK_HUMAN; Met-enkephalin-Arg-Gly-Leu; Met-enkephalin-Arg-Phe; Synenkephalin; PENK(114-133); PENK(143-183); PENK(237-258). |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 28kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PENK: 237-258/267 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015] Function: Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. Subcellular Location: Secreted. Post-translational modifications: The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. Similarity: Belongs to the opioid neuropeptide precursor family. SWISS: P01210 Gene ID: 5179 Database links: Entrez Gene: 5179 Human Entrez Gene: 18619 Mouse Omim: 131330 Human SwissProt: P01210 Human SwissProt: P22005 Mouse Unigene: 339831 Human Unigene: 475097 Mouse Unigene: 10015 Rat |
