| 產(chǎn)品編號 | bs-18198R |
| 英文名稱 | Rabbit Anti-MLR2 antibody |
| 中文名稱 | 配體依賴核受體共抑制因子抗體 |
| 別 名 | A630025C20RIK; FLJ38026; KIAA1795; LCoR; Lcor; LCOR_HUMAN; Ligand dependent corepressor; Ligand dependent nuclear receptor corepressor; Ligand-dependent corepressor; Mblk1 related protein 2; Mblk1-related protein 2; MLR2; RP11 175O19.1. |
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Specific References (1) | bs-18198R has been referenced in 1 publications.
[IF=1.664] Zhang PF et al. MicroRNA-139 suppresses hepatocellular carcinoma cell proliferation and migration by directly targeting Topoisomerase I. ONCOLOGY LETTERS 17: 1903-1913, 2019 WB ; Human.
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| 研究領(lǐng)域 | 細(xì)胞生物 染色質(zhì)和核信號 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 47kDa |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MLR2: 301-400/433 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008] Function: May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Similarity: Contains 1 HTH psq-type DNA-binding domain. SWISS: Q96JN0 Gene ID: 84458 Database links: Entrez Gene: 84458 Human Entrez Gene: 212391 Mouse Omim: 607698 Human SwissProt: Q96JN0 Human SwissProt: Q6ZPI3 Mouse Unigene: 729136 Human Unigene: 398778 Mouse Unigene: 422910 Mouse Unigene: 459119 Mouse |
