產(chǎn)品編號 | bs-18155R |
英文名稱 | Rabbit Anti-RELT/TNFRSF19L antibody |
中文名稱 | 腫瘤壞死因子受體超家族成員19L抗體 |
別 名 | Receptor expressed in lymphoid tissues; RELT; TNFRSF19L; Tumor necrosis factor receptor superfamily member 19L. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 43kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RELT/TNFRSF19L: 101-200/430 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008] Function: TNFRSF19L may be involved in T cell activation by mediation of the NF kappa B pathway. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cytoplasm Similarity: Belongs to the RELT family. Contains 1 TNFR-Cys repeat SWISS: Q969Z4 Gene ID: 84957 Database links: Entrez Gene: 84957 Human Entrez Gene: 320100 Mouse Omim: 611211 Human SwissProt: Q969Z4 Human SwissProt: Q8BX43 Mouse Unigene: 533720 Human Unigene: 40336 Mouse |