產(chǎn)品編號(hào) | bs-18122R |
英文名稱 | Rabbit Anti-IER3IP1 antibody |
中文名稱 | 即早反應(yīng)蛋白3相互作用蛋白1抗體 |
別 名 | HSPC039; IER3IP1; Immediate early response 3-interacting protein 1; IR3IP_HUMAN; PRO2309. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 轉(zhuǎn)運(yùn)蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 9kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human IER3IP1: 21-60/82 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
IER3IP1 has a G-patch domain which is thought to function in the binding of RNA. The G-patch domain is associated with various proteins which exhibit functions which may include tumor suppression and DNA damage repair, suggesting that IER3IP1 may be involved in cellular responses to DNA damage. Matrine is a molecule that induces erythroid cell differentiation of K562 cells and the presence of the IER3IP1 gene is thought to increase matrine function, implying a possible role for IER3IP1 in erythroid cell differentiation. Function: May be involved in protein transport between endoplasmic reticulum and Golgi apparatus. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Highest levels in heart, skeletal muscle, and kidney. Similarity: Belongs to the YOS1 family. SWISS: Q9Y5U9 Gene ID: 51124 Database links: Entrez Gene: 51124 Human Entrez Gene: 66191 Mouse SwissProt: Q9Y5U9 Human SwissProt: Q9CR20 Mouse |