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Rabbit Anti-MTMR7  antibody (bs-17888R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-17888R
英文名稱 Rabbit Anti-MTMR7  antibody
中文名稱 肌微管素相關(guān)蛋白7抗體
別    名 MTMR7; MTMR7_HUMAN; Myotubularin-related protein 7.  
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat (predicted: Human,Mouse,Rabbit)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 76kDa
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTMR7: 561-660/660 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Mar 2009]

Function:
Phosphatase that acts on lipids with a phosphoinositol headgroup.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed specifically in brain.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Contains 1 myotubularin phosphatase domain.

SWISS:
Q9Y216

Gene ID:
9108

Database links:

Entrez Gene: 9108 Human

Entrez Gene: 54384 Mouse

SwissProt: Q9Y216 Human

SwissProt: Q9Z2C9 Mouse

Unigene: 625674 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MTMR7) Polyclonal Antibody, Unconjugated (bs-17888R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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