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Rabbit Anti-MTMR1  antibody (bs-17881R)  
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產(chǎn)品編號 bs-17881R
英文名稱 Rabbit Anti-MTMR1  antibody
中文名稱 肌微管素相關蛋白1抗體
別    名 MTMR 1; Myotubularin related 1; Myotubularin related protein 1.  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 75kDa
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MTMR1: 31-130/665 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Function:
MTMR1 is a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. The MTMR1 gene shares structural similarities with the MTM1 gene, and is also located in the same chromosomal region. Myotubularin related proteins are a large subfamily of protein tyrosine phosphatases (PTPs) that dephosphorylate D3 phosphorylated inositol lipids. MTMR1 is a lipid phosphatase that acts on phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bisphosphate.

Subcellular Location:
Plasma Membrane; Peripheral membrane protein, cytoplasmic side.

Similarity:
Belongs to the protein-tyrosine phosphatase family.
Contains 1 GRAM domain.
Contains 1 myotubularin phosphatase domain.

SWISS:
Q13613

Gene ID:
8776

Database links:

Entrez Gene: 8776 Human

Entrez Gene: 53332 Mouse

Entrez Gene: 317296 Rat

Omim: 300171 Human

SwissProt: Q13613 Human

SwissProt: Q9Z2C4 Mouse

Unigene: 347187 Human



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