| 產(chǎn)品編號 | bs-17789R |
| 英文名稱 | Rabbit Anti-MRPL36 antibody |
| 中文名稱 | 乳腺癌易感基因1相互作用蛋白1抗體 |
| 別 名 | 39S ribosomal protein L36; 39S ribosomal protein L36 mitochondrial; BRCA1-interacting protein 1; BRIP1; L36mt; Mitochondrial ribosomal protein L36; MRP L36; MRP-L36; Mrpl36; PRPL36; Putative BRCA1 interacting protein; RM36_HUMAN; RPMJ. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 線粒體 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 12kDa |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MRPL36: 1-50/103 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008] Function: Component of the large subunit of the mitochondrial ribosome. Subcellular Location: Mitochondrion. Similarity: Belongs to the ribosomal protein L36P family. SWISS: Q9P0J6 Gene ID: 64979 Database links:
Entrez Gene: 64979 Human
Entrez Gene: 94066 Mouse
Omim: 611842 Human
SwissProt: Q9P0J6 Human
SwissProt: Q99N90 Mouse
Unigene: 719465 Human
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