產(chǎn)品編號(hào) | bs-17738R |
英文名稱 | Rabbit Anti-MPP8/MPHOSPH8 antibody |
中文名稱 | M期磷蛋白8抗體 |
別 名 | HSMPP8; M-phase phosphoprotein 8; M-phase phosphoprotein, mpp; M-phase phosphoprotein, mpp8; MPHOSPH8; MPP8_HUMAN; RP11-523H24.1; Twa3; Two hybrid-associated protein 3 with RanBPM. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse,Rhesus monkey) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 97kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MPHOSPH8: 601-700/860 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
MPHOSPH8 is a 860 amino acid nuclear protein that is phosphorylated in the M (mitotic) phase of the cell cycle. MPHOSPH8 contains four ANK repeats, motifs that are typically found in transcriptional regulators and cell cycle proteins and may be involved in protein-protein binding. Due to evidence suggesting that MPHOSPH8 forms a complex with Muskelin and Ran BP-M, a GTPase implicated in a diverse array of cellular processes, it may play a role in the Ran GTPase cycle. The gene encoding MPHOSPH8 resides on chromosome 13. There are two isoforms of MPHOSPH8 that are produced as a result of alternative splicing events. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated in M (mitotic) phase. Similarity: Contains 4 ANK repeats. Contains 1 chromo domain. SWISS: Q99549 Gene ID: 54737 Database links: Entrez Gene: 467217 Chimpanzee Entrez Gene: 54737 Human Entrez Gene: 75339 Mouse Omim: 611626 Human SwissProt: Q99549 Human SwissProt: Q3TYA6 Mouse |