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Rabbit Anti-Speedy protein C  antibody (bs-17660R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-17660R
英文名稱 Rabbit Anti-Speedy protein C  antibody
中文名稱 快速周期蛋白C抗體
別    名 hSpy/Ringo C; Rapid inducer of G2/M progression in oocytes C; Rapid inducer of G2/M progression in oocytes, Xenopus, homolog of, C; RINGO C; Ringo2; SPDYC; SPDYC_HUMAN; speedy C; speedy homolog C; Speedy protein C; Speedy, Xenopus, homolog of, C.  
研究領(lǐng)域 細胞生物  細胞周期蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33kDa
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Speedy protein C: 201-293/293 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2.

Function:
Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correctlocalization of the active form of Aurora B in prometaphase.

Subunit:
Interacts with CDK1 and CDK2. Interacts with AURKB.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis.

DISEASE:
Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis.

Similarity:
Belongs to the Speedy/Ringo family.

SWISS:
Q5MJ68

Gene ID:
387778

Database links:

Entrez Gene: 387778 Human

Omim: 614030 Human

SwissProt: Q5MJ68 Human

Unigene: 450642 Human



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