| 產(chǎn)品編號 | bs-17399R |
| 英文名稱 | Rabbit Anti-HSCB antibody |
| 中文名稱 | HSCB蛋白抗體 |
| 別 名 | AI325508; AW049829; dJ366L4.2; DnaJ (Hsp40) homolog, subfamily C member 20; DnaJ homolog subfamily C member 20; DNAJC20; Hsc20; HSC20_HUMAN; hscB; HscB iron sulfur cluster co chaperone homolog; Iron sulfur cluster co chaperone protein HscB mitochondrial; Iron-sulfur cluster co-chaperone protein HscB; J type co chaperone HSC20; JAC1; mitochondrial; RGD1311005; RP3-366L4.2. |
| 研究領域 | 細胞生物 信號轉導 新陳代謝 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human) |
| 產(chǎn)品應用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 24kDa |
| 細胞定位 | 細胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSCB: 101-200/235 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
HscB is a 235 amino acid mitochondrial protein that functions as a co-chaperone in iron-sulfur cluster formation. Highly expressed in heart, liver and muscle, and belonging to the HscB family, HscB exists as a L-shaped crystal structure resembling E. coli HscB. Human HscB contains an N-terminal mitochondrial targeting signal followed by a J-domain and short loop. The C-terminal domain folds into a compact 3-helix bundle and likely mediates specific interactions with IscU. Containing six exons and five introns, the gene encoding HscB maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Function: May act as a co-chaperone in iron-sulfur cluster assembly in mitochondria. Subcellular Location: Mitochondrion. Tissue Specificity: Liver, muscle and heart. Similarity: Belongs to the hscB family. Contains 1 J domain. SWISS: Q8IWL3 Gene ID: 150274 Database links: Entrez Gene: 150274 Human Omim: 608142 Human SwissProt: Q8IWL3 Human Unigene: 632780 Human |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
