| 產(chǎn)品編號(hào) | bs-17222R |
| 英文名稱 | Rabbit Anti-TOM1 antibody |
| 中文名稱 | TOM1蛋白抗體 |
| 別 名 | FLJ33404; OTTHUMP00000028777; Target of myb 1; TOM1_HUMAN； Target of Myb protein 1; Target of myb1; TOM 1. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 轉(zhuǎn)運(yùn)蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse,Chimpanzee,Rhesus monkey) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TOM1: 1-100/492 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] Function: TOM1 may be involved in intracellular trafficking. In conjunction with Tollip it plays an important role in recruiting clathrin onto endosomes and may modulate endosomal functions. Subunit: Interacts with ZFYVE16; interaction is required to target it to endosomes. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein Tissue Specificity: Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver Similarity: Belongs to the TOM1 family. Contains 1 GAT domain. Contains 1 VHS domain. SWISS: O60784 Gene ID: 10043 Database links: Entrez Gene: 10043 Human Entrez Gene: 21968 Mouse Entrez Gene: 717499 Rhesus monkey Omim: 604700 Human SwissProt: O60784 Human SwissProt: O88746 Mouse |
