產(chǎn)品編號(hào) | bs-16336R |
英文名稱(chēng) | Rabbit Anti-GSH2 antibody |
中文名稱(chēng) | GSH2蛋白抗體 |
別 名 | GS homeobox 2; GSX2; GSX2_HUMAN; Homeobox protein GSH 2; Homeobox protein GSH-2. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)運(yùn)蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 32kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GSH2: 211-304/304 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure. The homeobox DNA-binding domain is commonly found in proteins that play a role in development and are involved in transcriptional regulation and the control of gene expression. GSH-2 (GS homeobox-2), also known as GSX2, is a 304 amino acid protein that contains one homeobox DNA-binding domain. Localized to the nucleus, GSH-2 is thought to function as a transcription factor that selectively binds the DNA sequence 5'-CNAATTAG-3'. Specifically, GSH-2 may be involved in neuronal differentiation, playing a role in spinal cord development. Function: Probable transcription factor that binds to the DNA sequence 5'-CNAATTAG-3' (By similarity). Subcellular Location: Nucleus (By similarity). Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: Q9BZM3 Gene ID: 170825 Database links: Entrez Gene: 170825 Human Entrez Gene: 14843 Mouse SwissProt: Q9BZM3 Human SwissProt: P31316 Mouse Unigene: 371899 Human Unigene: 218752 Mouse |