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Rabbit Anti-GIPC3  antibody (bs-16246R)  
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產(chǎn)品編號(hào) bs-16246R
英文名稱 Rabbit Anti-GIPC3  antibody
中文名稱 19號(hào)染色體開放閱讀框64/C19orf64抗體
別    名 C19orf64; DKFZp686J1198; FLJ40925; GIPC 3; GIPC3_HUMAN ; GIPC PDZ domain containing family member 3; PDZ domain containing protein GIPC 3; PDZ domain containing protein GIPC3; PDZ domain protein GIPC 3; PDZ domain protein GIPC3.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GIPC3: 151-250/312 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the GIPC family. Studies in mice suggest that this gene is required for postnatal maturation of the hair bundle and long-term survival of hair cells and spiral ganglion in the ear. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2011]

Function:
GIPC3 is widely expressed in adult and fetal tissues. Highest levels are found in jejunum, lymph node, parietal lobe, fetal spleen and fetal thymus. It is expressed in cervical, melanoma, chronic myelogenous and gastric cancer cell lines.

Tissue Specificity:
Widely expressed in adult and fetal tissues. Highest levels are found in jejunum, lymph node, parietal lobe, fetal spleen and fetal thymus. Expressed in cervical, melanoma, chronic myelogenous and gastric cancer cell lines.

DISEASE:
Deafness, autosomal recessive, 15 (DFNB15) [MIM:601869]: A form of non-syndromic sensorineural hearing loss with prelingual onset. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the GIPC family.
Contains 1 PDZ (DHR) domain.

SWISS:
Q8TF64

Gene ID:
126326

Database links:

Entrez Gene: 126326 Human

Omim: 608792 Human

SwissProt: Q8TF64 Human

Unigene: 266873 Human



產(chǎn)品圖片
Sample: K562 (Human)Cell Lysate at 40 ug Hela(Human) Cell Lysate at 40 ug Primary: Anti-GIPC3(bs-16246R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 30kD
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