產(chǎn)品編號 | bs-16216R |
英文名稱 | Rabbit Anti-Galantide antibody |
中文名稱 | 甘丙肽受體拮抗劑抗體 |
別 名 | Galanin receptor antagonist; Reversible galanin receptor antagonist; M15. |
產(chǎn)品類型 | 小分子抗體 |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 通道蛋白 G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 2kDa |
細(xì)胞定位 | 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide of Galantide: 1-20/20 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The galanin antagonist Galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C terminal fragment of bradykinin, has been found to improve social memory in `social recognition' tests when i.c.v. administered at doses varying from 6-6000 nmoles. Galantide causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose induced insulin secretion. Subcellular Location: Secreted. SWISS: N/A CAS: N/A Database links:
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