| 產(chǎn)品編號(hào) | bs-16201R |
| 英文名稱 | Rabbit Anti-FXL19 antibody |
| 中文名稱 | FXL19蛋白抗體 |
| 別 名 | F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19; FBL19; Fbxl19; FXL19_HUMAN; JHDM1C; Jumonji C domain containing histone demethylase 1C. |
| 研究領(lǐng)域 | 細(xì)胞生物 跨膜蛋白 泛素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 76kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FXL19: 401-500/694 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Subunit: Directly interacts with SKP1 and CUL1 (By similarity). Similarity: Contains 1 CXXC-type zinc finger. Contains 1 F-box domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 PHD-type zinc finger. SWISS: Q6PCT2 Gene ID: 54620 Database links: Entrez Gene: 54620 Human Entrez Gene: 233902 Mouse GenBank: BC059173 Human Omim: 609085 Human SwissProt: Q6PCT2 Human SwissProt: Q6PB97 Mouse Unigene: 152149 Human |
