產(chǎn)品編號(hào) | bs-16064R |
英文名稱 | Rabbit Anti-FCRL1 antibody |
中文名稱 | CD307a抗體 |
別 名 | CD307a; Fc receptor homolog 1; Fc receptor like protein 1; Fc receptor-like protein 1; FcR like protein 1; FcR-like protein 1; FCRH 1; FcRH1; FCRL 1; FcRL1; FCRL1_HUMAN; hIFGP 1; hIFGP1; IFGP 1; IFGP family protein 1; IFGP1; Immune receptor translocation associated protein 5; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA 5; IRTA5; RP11 367J7.7. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 45kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FCRL1: 251-350/429 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] Function: May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level). Post-translational modifications: Phosphorylated on tyrosines upon activation. Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains. SWISS: Q96LA6 Gene ID: 115350 Database links: Entrez Gene: 115350 Human Omim: 606508 Human SwissProt: Q96LA6 Human Unigene: 656112 Human |